منابع مشابه
The Cancer Stem Cell Hypothesis in Oral Squamous Cell Carcinoma: A New Target for the Treatment
Within a single tumor clone, cells have significantly different abilities to proliferate and form new tumors. This has led to the hypothesis that most cells in a cancer have a limited ability to divide and only a small subset of distinct cells, the cancer stem cells (CSCs), has the capacity to self-renew and form new tumors . It has been proposed that the development of tumors is based exclusiv...
متن کاملInvestigation of Stem Cell Aging Throughout the Lifetime and Therapeutic Opportunities
Introduction: Aging is a natural phenomenon that is caused by changes in the cells of the body. Theoretically, aging starts from birth and lasts throughout life. These changes affect the function of the cells. Also, in old tissues, the capacity for homeostasis and tissue repair is decline due to destructive changes in specific tissue stem cells, niche of stem cells and systemic factors that reg...
متن کاملStem cell aging.
202 W E summarize here the fruitful discussion that occurred on a wide variety of topics during the session on stem cell aging. Somatic Stem Cell Aging Do stem cells age; and if they do, how can these changes be reliably identifi ed? Most attendees were of the view that a decline in the function of tissue-specifi c somatic stem cells is likely to play an important role in human aging. Results f...
متن کاملReversing stem cell aging
The stem cell theory of aging postulates that aging is the result of the failure of tissue specific stem cells to replenish tissues and to sustain tissue function. Stem cell functions decline with age, consistent with the degeneration and dysfunction of aging regenerative tissues. Stem cell dysfunction is associated with premature aging and evidence is emerging to suggest that stem cell manipul...
متن کاملHematopoietic stem cell aging.
Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In this review, we summarize current aspects ...
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ژورنال
عنوان ژورنال: The Indonesian Biomedical Journal
سال: 2010
ISSN: 2355-9179,2085-3297
DOI: 10.18585/inabj.v2i1.108